Categories: PhD

Phd Position: In Oral Microbial Biofilm Management @ KU Leuven

Share

Ph.D. Position: Pro- And Prebiotics In Oral Microbial Biofilm Management

The Laboratory for Oral Microbiology (Periodontology section, Department of Oral Health Sciences, Faculty of Medicine, KU Leuven) is searching for a talented Ph.D. student for translational research in the field of oral microbiology. With an aim to further unravel the potential of probiotics and prebiotics in oral biofilm modulation in relation to periodontal diseases. The lab has pioneered the use of probiotics and prebiotics for oral health care both at a clinical and a basic science research level. The lab has a strong background in oral microbiology, biofilm formation and interaction between the oral microbiota and host cells.

Employment percentage: Full-time
Location: Leuven, Periodontology & Oral Microbiology
Apply before: Saturday, September 15, 2018

Project

Dental plaque is a bacterial biofilm which can lead to tooth decay and periodontitis. Not all bacteria in dental plaque contribute to these diseases as they will only develop when specific pathogens become numerically dominant in dental plaque. It should not be surprising that also these pathogens are becoming more and more resistant towards antibiotics but also to antiseptics. Therefore alternative treatment or preventive options should be explored. The outgrowth of pathogens during disease development is mirrored by a proportional reduction in certain beneficial/commensal bacteria. Group has shown both in vivo and in vitro that probiotics help to suppress this outgrowth of pathogens. Additionally, the group has shown that certain substrates (prebiotics) can modify biofilm composition by stimulating commensal bacteria. Therefore this project aims at:

  1. finding substrates and probiotics that can increase the activity of beneficial/commensal bacteria,
  2. Evaluate the effect of these substrates and probiotics on biofilm composition,
  3. Virulence gene expression within biofilms,
  4. Inflammatory potential of modified biofilms.

These aspects will be evaluated in 3 different clinically relevant biofilm models.

Offer

The Ph.D. candidate will get a full-time fellowship for 4 years (with a probation period of 6 months) in an intellectually challenging environment and state-of-the-art facilities.

Interested?

For more information please contact Prof. dr. Wim Teughels, tel.: +3216332505, mail: wim.teughels@kuleuven.be.
You can apply for this job no later than September 15, 2018, via the online application tool
BioTech Times Desk @https://twitter.com/BioTech_Times

BioTech Times is the leading digital media covering the biotech sector. You can find latest updates on business and innovations in biotechnology, jobs, notifications, and articles for competitive exams.

Published by

Recent Posts

Science & SciLifeLab Prize for Young Scientists

The Science & SciLifeLab Prize for Young Scientists is a global prize, aimed at rewarding scientists at an early stage of their…

12 hours ago

Microbiology Research Associate Post @ Vasantdada Sugar Institute Pune

Microbiology Research Associate Posts available for eligible candidates at Department of Alcohol Technology, Vasantdada Sugar Institute Pune.

2 days ago

WII Govt Life Sciences & Biotechnology Project Personnel Recruitment

Wildlife Institute of India (WII), Dehradun is hiring 23 research personnel through a Qualifying test to be held on 23rd…

2 days ago

ICAR-IINRG Research Fellow Position | Work in DBT – Bio-CARe Project

ICAR-Indian Institute of Natural Resins & Gums is recruiting for Life Sciences/ Biochemistry/ Biotechnology Junior Research Fellow.

2 days ago

Life Sciences & Biotechnology JRF Job @ Vector Control Research Centre

Job seekers with MSc Life Science/ Biochemistry/ Biotechnology/ MolecularBiology/ Bioinformatics are eligible to apply for JRF at ICMR-VCRC.

3 days ago

ICAR-NBFGR Biotechnology/ Bioinformatics/ Life Sciences Research Jobs

A walk-in-interview is scheduled at ICAR-National Bureau of Fish Genetic Resources (NBFGR), Lucknow for selection of various research posts.

3 days ago